Downloads

Polygenic risk modeling with latent trait-related genetic components

Below are downloads corresponding to "Polygenic risk modeing with latent trait-related genetic components" (Aguirre, et. al.; bioRxiv forthcoming). Methods and downloads descriptions for these supplementary files can be found in the manuscript.

• List of analysis phenotypes: Degas-Risk-Phenotypes.tsv
• DeGAs model weights: all_z_center_p001_20190805_500PCs.npz (~1.8GB)
• Performance summary: degas-risk-results-v1.tar.gz
• Component contribution plots: For Traits and Genes
• README will be posted soon. Check back for updates!

Summary-level data from CNV associations

Below are downloads corresponding to "Phenome-wide Burden of Copy Number Variation in UK Biobank" (Aguirre MA, Rivas MA, Priest JR; bioRxiv 545996). Description of methods used for analysis and available data can be found in the manuscript and in the readme below.

• Readme: README.txt
• List of phenotypes with available data: pheno_index_v2.20190513.txt
• CNVs Called: cnv.ukb.reference_v2.20190626.txt (~31MB)
• Summary Stats: cnv.assoc.release_v2.20190513.tar.gz (~1.9GB)